flexEO - Portable device based on flexible electronics and optics for in vivo spectrometry of blood components for telemedicine
Blood spectrometry (BSP) generally allows a quantitative determination of blood components. In the context of an increase in chronic diseases and a pronounced multimorbidity, but also in view of the growing willingness for private prevention and fitness applications, a non-invasive, in vivo BSP has countless clinical and non-clinical applications. In contrast to in vitro BSP, which is state-of-the-art today, in vivo BSP has not yet been sufficiently implemented. The difficulty lies in the fact that secondary, static (skin and bone) and dynamic influencing factors (blood pulsation) determine in vivo detectable spectra and prevent an analysis of the blood components.
One focus of the project is the development of a portable device containing a microspectrometer developed by anvajo for recording the absorption spectra and an electronic unit based on flexible substrates of the Faculty of Electrical Engineering of the TU Dresden. In order to meet the challenge of robust biosignal acquisition, even under difficult conditions (movement, etc.), new, innovative hardware solutions are implemented.
The project is funded by the EU within the framework of the ERDF programme and runs until the end of 2019. The project executing agency is the Sächsische Aufbaubank.
GlyHo - Glyphosate Trace Detection in Aqueous Systems and Food by Holographic On-Site Analysis
Low molecular weight trace substances in aqueous systems with their origin in agricultural use, such as the broad spectrum herbicide glyphosate, are very critically discussed in society due to their potential danger to human health. Not only do they potentially endanger the health of the population, but they also affect the biodiversity of natural ecosystems. Sensitive analytical methods for the detection of these micropollutants have the problem of requiring complex and expensive laboratory diagnostics and/or insufficient sensitivity and specificity for low molecular weight analytes.
The R&D project is developing a new on-site analysis system for the detection of glyphosate in aqueous systems. The new technology is jointly developed by the Saxon companies anvajo, UMEX and IfU together with the Institute of Genetics of the TU Dresden and the Institute of Biochemistry of the University of Leipzig. Through the use of microfluidic technologies, holographic optical detection methods and biospecific functionalization of microparticles and chip surfaces, a method is being developed which will be made available for food monitoring, environmental monitoring and consumer applications as a mobile on-site analysis system for various applications.
The project brings together the expertise available in the Saxon SMEs and at the two Saxon universities and, if successful, forms a platform technology for a new type of easily manageable on-site analysis systems, which can be used in various applications for a wide range of users and economically marketable.
The project is funded by the EU within the framework of the ERDF programme and runs until the end of 2021. The project executing agency is the Sächsische Aufbaubank.